Evidence supports a cause-effect relationship between exposure to the air and dust in water-damaged buildings (WDBs) and chronic inflammatory response syndrome (CIRS). This syndrome has an increased relative risk associated with specific HLA genotypes.
Read MoreAt first, one might not associate environmental exposures with pain. Warm climate versus cold caus- ing pain? Humid climate versus dry causing pain? Urban versus rural? Pain isn’t the first response a physician might necessarily associate with environmental exposures.
Read MoreEvidence has accumulated since 2008 that intranasal, topical application of vasoactive intestinal polypeptide (VIP) can be administered safely to patients with a multi-system, multisymptom illness, called chronic inflammatory response syndrome (CIRS), acquired following exposure to biologically produced toxins and inflammagens.
Read MoreExposure to the microbial growth in Water Damaged Buildings (WDB) can result in a chronic, multi-symptom, multisystem illness, which can last years, termed Chronic Inflammatory Response Syndrome (CIRS).
Read MoreCiguatoxins (CTXs) are polyether marine neurotoxins found in multiple reef-fish species and are potent activators of voltage-gated sodium channels. It is estimated that up to 500,000 people annually experience acute ciguatera poisoning from consuming toxic fish and a small percentage of these victims will develop a chronic, multisymptom, multisystem illness, which can last years, termed a Chronic Inflammatory Response Syndrome (CIRS).
Read MoreExecutive cognitive and neurologic abnormalities are commonly seen in patients with a chronic inflammatory response syndrome (CIRS) acquired following exposure to the interior environment of water-damaged buildings (WDB), but a clear delineation of the physiologic or structural basis for these abnormalities has not been defined. Symptoms of affected patients routinely include headache, difficulty with recent memory, concentration, word finding, numbness, tingling, metallic taste and vertigo.
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